In 1733, Lady Mary Wortley Montagu significantly advanced public health by introducing variolation to Western society. During her time in the Ottoman Empire, she learned of this smallpox inoculation method and, witnessing its success, became an advocate for its use in England. Montagu's promotion of the technique—including inoculating her own children—paved the way for reduced smallpox mortality and influenced subsequent vaccination developments, marking a pivotal moment in medical history.
