In a reality where Fermi's paradox is all too real, man has exhausted local real estate, and has therefore started the seeding and terraforming alien worlds.
Making them hospitable for hosts such as themselves. Expedited evolution, modifying and adapting the genome of the selected seed-structures. Greatly enhancing the chances of successful development of an intelligible consciousness (preferably mammalian, even though this is not always the case). A severe factor of unexpected turns are present though, when so many agents are in play; be it either because of overlooked “locals”. Further manipulation (the god complex is all too real), or aberration of protocol.
